For its muscle-building properties, Ibutamoren is frequently discussed online forums. It is available on the counter and used by those who want to increase their levels of growth hormone. However, there are relatively few clinical studies of this compound. We’ll highlight what’s known so far about ibutamoren in the text below. Ibutamoren (also known as ibutamoren mesylate or MK-677), promotes growth hormone (GH) secretion and increases the growth factor 1 (IGF-1) of insulin[ R, R].
Ibutamoren increases levels of growth hormone by mimicking hormone ghrelin action and binding to one of the brain’s ghrelin receptors (GHSR). GHSR activated stimulates the release of growth hormones.
Building muscle ibutamoren is often used as an anabolic substance to increase the mass of the lean body, i.e. to create larger muscles. It’s active orally and can be taken once a day.
Compared to other growth hormone stimulators, these are all advantages. As mentioned earlier, ibutamoren increases levels of growth hormone and IGF-1. In turn, both growth hormone and IGF-1 increases muscle mass, muscle strength, and reduces body fat[ R, R]. A two-month treatment with ibutamoren (double-blind randomized controlled trial) increased lean mass in 24 obese men and transiently increased basal metabolic rate (BMR).