Andarine has a high affinity to the androgen receptor and thus mimics testosterone effects. Its effects in muscles and bones, however, are much stronger than in reproductive organs.
This drug has been developed to prevent muscle wasting, and indeed animal studies show that Andarine improves muscle growth and animal strength. Andarine increased muscle weight as markedly as DHT (dihydrotestosterone) when given to castrated rats for 4 weeks. In addition, Andarine did not cause prostate enlargement unlike DHT, which is a concern when takingsteroids. Andarine was able to restore lean body (muscle) mass in rats twelve weeks after castration.
Andarine increased bone mineral density and strength in both castrated male rats and female rats whose ovaries have been removed (this is a commonly used animal model of osteoporosis.
Andarine may be particularly beneficial in osteoporosis because it also improves muscle strength in addition to enhancing bone density, which can help reduce the risk of falls and fractures.